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Ongoing physician supervision is standard practice, not optional

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The only human trial ever registered (NCT02637284) was cancelled in 2016 without publishing results

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Other groups that are at a greater threat of having a vitamin B12 deficiency consist of cigarette smokers (given that nicotine could obstruct absorption), alcoholics, those with anemia, and any individual with a gastrointestinal condition like Celiac or Crohns illness