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Additionally, UA has demonstrated neuroprotective effects against oxidative stress caused by hydrogen peroxide (H2O2), thereby safeguarding neuronal survival in the face of elevated levels of reactive oxygen species (ROS) (Figure 5)

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We also asked if genetically increasing the glutaryl-CoA pool (the donor for glutarylation) altered glutaryl modifications and generated GCDH-deficient HeLa cells (Supplementary Fig