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This expansion or duplication of genes resulted in sequence variations that expanded substrate functionality and/or responses to environmental stresses [62, 70, 71]

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In addition, studies have shown that during the adult liver progenitor cells (HPC)/oval cells involved in the repair of chronically injured livers, the HGF/c-Met pathway plays a crucial contribution in regulating TGF--mediated epithelial-mesenchymal transition (EMT) responses

Br J Anaesth 111(4):589593