sally tobacco #2 soft texture. *Sally enters smoking a cigarette*

Apparently there were other answers in this grid, but the whole name change / gender change DORIS MILLER extravaganza really made the rest of the puzzle kind of disappear

Beta blockers are widely prescribed and effective but can cause increased fatigue and decreased exercise tolerance because they prevent an increased heart rate as a normal response to physical activity

Smoking increases miscarriage risk in pregnant women, causes premature births, reduces birth weight, and raises the risk of sudden infant death syndrome by up to three times

Cognac and brandy are great options for pairing

The initial draw delivers a crisp, natural menthol kick, which can be enhanced by crushing the grape/berry-flavored capsule in the cigarette-filter