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As a potent endogenous antioxidant, BR not only effectively scavenges superoxide and helps cells partially resist oxidative stress, but also possesses significant iron chelating ability, which effectively chelates Fe 2+ and Fe 3+ , alters the distribution of intracellular iron, and reduces the cellular uptake of iron, thus constituting an important part of the endogenous antioxidant defense system (Llido et al., 2023)

Transcriptomic RNA-seq analysis revealed that oxidative stress-related signaling pathways were upregulated in lung cancer cells (PC-9, NCI-H1975) following Cu-DMSA-HA treatment (Figs

Beta-blockers, cimetidine, and halothane increase lidocaine plasma concentrations, requiring a reduction in lidocaine dosage (11)

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