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Hypoxia : The production of your red blood cell raises to make up for the chronically low blood oxygen levels owing to poor lung or heart function

These findings unveil a distinct regulatory axis in which nutrient sensing by astrocytes fine-tunes inflammatory and oxidative responses at the level of protein translation, revealing a novel mechanism by which substrate availability modulates enzyme activity during neuroinflammation 123

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May 2012;69(5):1213-1220