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Response: We appreciate the commenters' remarks as to the importance of maintaining the ability of the physician/NPP to make changes to a patient's POC outside of the 10-day window, as noted at 410.61(d), if we were to adopt this 10-day window policy

Drug Interactions Because these peptides influence vascular, inflammatory, and neurological pathways, interactions with anticoagulants, NSAIDs, immunosuppressants, psychiatric medications, and other pharmaceutical agents are possible but largely unexplored