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In contrast, aPC exerts different effects on PARs

doi: 10.1084/jem.192.4.571 26 KerrJFWyllieAHCurrieAR

Glycine may also become limiting in some people, particularly with aging or inadequate protein intake

[1] [2] Testosterone, by contrast, is a well-established androgen hormone used therapeutically in the UK for conditions such as confirmed hypogonadism and, under specialist supervision, as part of gender-affirming hormone therapy (which is generally considered off-label use in the UK and requires specialist oversight)