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The pK a of Tyr9 is 8.1 in the free GST A1-1, but the value increases to 9.2 when glutathione is bound ( a appears dependent on the ionized thiolate, since S-methylglutathione is without effect on the ionization of Tyr9

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

Microglial interactions with the neurovascular system in physiology and pathology

According to the formula, there are 2 2 = 4 possible stereoisomers, whose structures are depicted in the accompanying figure as Fischer projections, labeled A, B, C, and D