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Causes of B12 Deficiency Although the requirements of B12 are quite small, it has a complicated absorption process in the digestive tract and, therefore, certain conditions make a B12 deficiency more common

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Commercially available CD38 mAbs for MM treatment include daratumumab (fully human, approved by FDA in 2015 and by EMA in 2016) and isatuximab (fully human, approved in 2021)

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