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Hereditary forms of AD are caused by mutations in the A precursor protein, APP, or in the presenilins, which are part of the multi-protein complex involved in A generation (Ringman et al., 2014)

As lipid peroxidation is a defining characteristic of ferroptosis, we carried out untargeted lipidomics analysis in SK-MEL-103 cells undergoing etoposide or tozasertib-induced senescence (Fig