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doi: 10.1016/j.smim.2017.12.004

hypoxia, wound fragments misadaptation, infection) tend to hamper this process resulting in scar formation or delayed healing, and probably induce VEGF formation by more than one mechanism (22)

Furthermore, elevated nasopharyngeal NTHi bacterial load can result in a clinically significant increase in COPD symptoms, even in the absence of a clinical exacerbation (Pettigrew et al., 2012)