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However, these changes were not correlated with disease motor severity 147

The incorporation of 2-aminoisobutyric acid at position 8 made the molecule completely resistant to DPP-4 cleavage when incubated with recombinant enzyme for 24 h, while native GLP-1 lost 50% activity within minutes [32,38]

Various marine natural products with anti-protozoal activity have been reported in the literature (Watts et al., 2010

CHMP2A In a TCT screen in GBM cells, where GBM cells transduced with CRISPR KO libraries and co-cultured with NK cells, CHMP2A was found to sensitize GBM to NK cells