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Short-term Western diet intake promotes IL-23mediated skin and joint inflammation accompanied by changes to the gut microbiota in mice

hold reconstituted material at 2-8C

The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

Randomized trials have shown that folate and other nutritional supplementations have a significant effect in treating the treatment-resistant depression [19,20]

Current investigations are focused on understanding whether NNMT inhibition might influence cancer progression or aggressiveness