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doi: 10.3892/mco.2017.1247 32 SampathDCortesJEstrovZDuMShiZAndreeffMet al

Adverse outcome pathways and drug-induced liver injury testing

2017;17(1):196 Definitions Antioxidant -a compound that prevents or repairs the damage caused by reactive oxygen species Congestive heart failure - when heart failure is accompanied by fluid build-up in the lungs, liver, gastrointestinal tract, and limbs

Thus, direct inhibition of GSH synthesis would be predicted to induce ferroptosis

To determine if persistent BPA-induced alterations to retinal physiology are associated with perturbations to E 2 genomic signaling as we observed in adults following a 24 hr BPA exposure (Fig