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They are subject to cosmetic labeling and safety rules, not pharmaceutical standards

The occurrence of these phenomena can be attributed to two main aspects: (i) the host burden caused by the massive production of RPs [16] and (ii) the limited post-translational modification (PTM) capacity and generation of inclusion bodies (IBs) [17]

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As islet macrophages constantly probe their microenvironment for signals, they sense these fluctuations in -cell activity, via uptake of insulin-containing vesicles or through overactivation of their purinergic receptors by ATP