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Gene expression alterations in doxorubicin resistant MCF7 breast cancer cell line

Low-molecular-weight polyamines such as putrescine, spermidine, and spermine are amino acid-derived polycationic alkylamines involved in the regulation of cell growth, proliferation, and differentiation (92)

It is also less sticky and more cosmetically elegant than normal HA, so no wonder the nickname of this molecule is super hyaluronic acid

One study elucidated a link between mutations in optineurin with pathology of primary open-angle glaucoma, emphasizing evidence of impaired mitophagy leading to the accumulation of damaged mitochondria (Shim et al., 2016)