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[7] Narcolepsy type 1 features EDS with either cataplexy or cerebrospinal fluid (CSF) orexin levels of less than 110 pg/ml, but most cases present with both

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2002 Jun;12(2):125-35

204 Similarly, administration of the PRMT5 inhibitor PJ-68 in a CML mouse model with high expression of PRMT5 LSCs could deplete DVL3, thereby inhibiting Wnt/-catenin signaling and significantly prolonging the survival time of a retroviral BCR-ABL-driven CML mouse model

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