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In controlled lighting studies involving rodents subjected to constant illumination (a stressor that disrupts circadian patterns), intermittent Epithalon treatment normalized melatonin and cortisol rhythms, partially preserving typical daynight physiological cycles [2][4][5]

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(Of note, Life Extension is the only one of our milk thistle recommendations that specifies silybin content.) Whats more, the company that makes Siliphos, Indena, has conducted a handful of studies on it, which we cover in greater detail down in Life Extensions dedicated section

Lab work allows us to personalize dosing, monitor progress, and ensure therapy is both safe and effective

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