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Description

Threonine binding to TARS2 causes its association with GTP-bound RagC, and subsequent activation of the RagA-RagC dimer, leading to activation of mTORC1 (Kim et al., 2021)

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10.1007/s10815-010-9471-y 36

The interaction between the HOMO of a nucleophile and the LUMO of an electrophile is a key factor in determining the reactivity and selectivity of organic reactions