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Shabany M

doi: 10.1039/C7SM01687E

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TP53 pathway alterations drive radioresistance in diffuse intrinsic pontine gliomas (DIPG)

In keeping with this idea, the tripeptide L--glutamyl-L-cysteinyl-glycine, or glutathione (GSH), a ubiquitous thiol, plays an important role in maintaining intracellular redox equilibrium and has evolved as one of the major detoxifying antioxidants and abundant thiols in almost all mammalian cells [13, 14, 40, 41, 4750]