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Folate and other one-carbon metabolism-related nutrients and risk of postmenopausal breast cancer in the Cancer Prevention Study II Nutrition Cohort

When combined with 5-Amino-1MQ, which inhibits NNMT (nicotinamide N-methyltransferase) to preserve NAD+ pools, the two compounds target overlapping but mechanistically distinct pathways

Herrmann and Obeid, 2012), but multiple laboratory investigations can be performed

It has never received FDA approval and is classified as a research compound