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L.VosT.LozanoR.NaghaviM.FlaxmanA

In addition to the G q/11 pathway, the G i/o pathway has also been shown to be recruited by the ghrelin receptor

Increased GSTP1 expression in ovarian tumours ( n =41), relative to unmatched healthy ovarian samples ( n =12) and benign tumours ( n =25) has been described in a small Chinese study (Cheng et al, 2000) and, consistent with our findings, GSTP1 expression in ovarian cyst fluid has been correlated with higher relapse rates following platinum-based chemotherapy (Boss et al, 2001)

However, patients receiving pharmacologic doses of niacin (500 mg or higher) for lipid modification require closer monitoring due to niacin's known effects on insulin sensitivity and glucose homeostasis

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