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10.1016/j.jtcme.2018.06.001

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Therefore, timing, dosage, and purpose of glutathione administration are critical

To further investigate how ferroptosis could affect glia cells in AD, we looked at the difference in expression of ferroptosis-related genes in microglia between control and AD brains containing only amyloid- plaques in the occipital cortex (OC) and both amyloid- and tau pathology in the occipitotemporal cortex (OTC) ( p -value below 0.05 was used to determine the significance (Table 2)