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The key factor affecting the switch from antioxidant to prooxidant properties of carotenoids has been attributed to the partial pressure of oxygen, typically high in the lungs

Glutathione is the most abundant intracellular antioxidant, not only providing protection against reactive oxygen and nitrogen species, but also playing a major role in multiple functions that maintain cellular homeostasis

Despite the sample size being low ( N = 32) and these results may be attributed to differences in their dietary patterns, the authors observed that these microbial changes appear to contribute to the pathogenesis of BD