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In light of these results, clinicians should consider the potential benefits of Ang-II stimulating AHMs, relative to Ang-II inhibiting AHMs, for hypertensive patients, especially those at higher risk for dementia

Additional information Peer review information Nature Communications thanks David Binks and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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By quieting glutamate signaling while enhancing GABA, DSIP creates conditions favorable for deep sleep without completely suppressing brain activity