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As discussed above (in the section Role of mitochondria in synaptic transmission), Ca 2+ signaling is involved in the accumulation of mitochondria at the postsynaptic regions, where these organelles participate in neuronal Ca 2+ buffering and support of neurotransmission [93]

We identified Y211 as another residue of interest as it forms part of the carnitine binding site and is one residue downstream Na + -coordinating N210 on TM4

L-carnitine supports your heart by supporting already-healthy blood pressure and helping to maintain healthy body fat composition

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Although concomitant medication changes were not recommended throughout the study period, adjustments in antihypertensive and antidiabetic treatments were conceded in selected cases to avoid acute clinical complications during the trial