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Activated kinases, such as ERK and Akt, can regulate ER activity through phosphorylation 81 , supporting the observed differential effects of BPA on ER-mediated gene expression of estrogen target genes

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Yanni 3 , Rohit Kohli 4 and Juliet Emamaullee 5 , (1)Children's Hospital Los Angeles, Los Angeles, CA, (2)University of Southern California, (3)Children's Hospital Los Angeles, (4)Childrens Hospital Los Angeles, Los Angeles, CA, (5)University of Southern California, Los Angeles, CA Background: Pediatric acute liver failure (PALF) remains a poorly-characterized disease entity that affects children of all ages

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Wilsons disease in patients presenting with liver disease: a diagnostic challenge