This appears to be a mechanism for a physiological toxic agent, since HOCl is a strong oxidant that acts as a bactericidal agent in phagocytic cells
The quantification of substances reacting with thiobarbituric acid was assessed by comparing the absorbance with the standard curve of MDA equivalents, generated through the hydrolysis of 1,1,3,3-tetramethoxypropane with acid catalysis (Enis Yonar et al., 2011)
146 These findings position ERAD as a critical safeguard of endocrine pancreatic function and a potential therapeutic target for diabetes
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