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Importantly, co-treatment with PWE effectively normalized the expression of all three markers, restoring PECAM-1, NRF2, and HO-1 protein levels to values comparable to controls (Figures 6A,B)

Apparently, after sensitization, T-cells are less capable of recirculating through the lymphoid organs, but gain ability to migrate into the peripheral tissues

Involvement of immune system in COVID-19 and insulin resistance Immune system is one of the first to react to the COVID-19 infection and both the innate and adaptive immune systems may suffer from the infection of SARS-CoV-2 with unique acute and prolonged residual effects

This is a conflict of interest that does not invalidate the research but requires independent confirmation, which has been limited

SHIMOMURA, M., YOSHIMATSU, F., & MATSUMOTO, F