Cao D, Shen K, Li Z, Xu Y, Wu D
But given the high GSH intracellular concentration (110 mM) in most cell types, this still accounts for ~50500 M thiolate concentration
Changing the amount of lipids, the type of lipids, cholesterol: lipid ratio or more than one factor may significantly affect the transfection efficiency or the vaccines pharmacokinetic properties, thus changing the required dose
Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations BMI: Body mass index CAT: Catalase COPD: Chronic obstructive pulmonary disease Cu-Zn-SOD: Copper, zinc superoxide dismutase CVD: Cardiovascular diseases DM2: Type 2 diabetes mellitus DNA: Deoxyribonucleic acid DNPH: 2,4-dinitrophenylhydrazine Fe-SOD: Iron superoxide dismutase FMOC: 9-fluorenylmethoxycarbonyl hydrazine GPx: Glutathione peroxidase GPx-1: Glutathione peroxidase 1 GPx-2: Glutathione peroxidase 2 GPx-3: Glutathione peroxidase 3 GPx-4: Glutathione peroxidase 4 GR: Glutathione reductase GSH: Reduced glutathione GSSH: Oxidized glutathione H 2 O 2 : Hydrogen peroxide Hb: Hemoglobin HPLC: High-performance liquid chromatography KCN: Potassium cyanide LDL: Low-density lipoproteins LP: Lipid peroxidation M1dG: 3-(2-deoxy--d-erythro-pentafuranosyl) pyrimido[1,2-]purin-10(3H)-one deoxyguanosine MDA: Malondialdehyde Mn-SOD: Manganese superoxide dismutase NADPH: Nicotinamide adenine dinucleotide phosphate NU: Nitrite units O 2 -: Superoxide anion PUFA: Polyunsaturated fatty acids ROS: Reactive oxygen species SNP: Single-nucleotide polymorphism SOD: Superoxide dismutase SOD1: Superoxide dismutase 1 SOD2: Superoxide dismutase 2 SOD3: Superoxide dismutase 3 TBA: Thiobarbituric acid TBARS: Thiobarbituric acid reactive substances TXA2: Thromboxane A2 U/g Hb: Units per gram of hemoglobin References Aebi H
In this application note, Promega presents the new P450-Glo CYP2B6 luminogenic assay characterization and demonstrate its utility for measuring both CYP2B6 inhibition and induction
