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Supplementary Table S3 summarizes the proteomic methodologies discussed, highlighting their principles and applications in CF oxidative stress research

Current treatments targeting single inflammatory mediators may have limited efficacy due to redundancy within the innate immune system and the potential for eventual immunosuppression

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The mediators of cartilage damage include MMPs, a disintegrin-like metalloprotease with thrombospondin type 1 motifs 4 and 5 and cathepsins

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