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The opposite effect of CK1 in erythroid precursors and mature RBCs might be explained by the lack of the caspase-10-Bid axis in erythrocytes, which is at least partly responsible for anti-apoptotic action of CK1 in the erythroid precursors

The effect of PA on the modulation of liver function was in harmony with the results of Xu et al

Latif S, Jahangeer M, Maknoon Razia D et al (2021) Dopamine in parkinsons disease

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Consequently, pigmentation gradually reduces, and the skin regains a brighter, more even-toned appearance