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(2) Centro Universitrio De Belo Horizonte, Belo Horizonte, MG, Brasil Diabetology & Metabolic Syndrome 2026: PO047 Introduction : Diabetes mellitus (DM) is one of the main public health challenges, associated with high morbidity and mortality and the risk of chronic disabling complications such as peripheral diabetic neuropathy, which is an important risk factor for the development of diabetic foot, a condition associated with ulcers, infections, and amputations

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The triple agonism is achieved through a combination of conserved interactions and receptor-specific contacts within the transmembrane domain