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In summary, artesunate acts by reducing M1 macrophage activation and suppressing the RIPK1/RIPK3/MLKL signaling cascade through the downregulation of Mincle expression, thereby diminishing the inflammatory response and necroptosis, which contributes to improvement of renal injury in AKI

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10.1016/j.conb.2019.01.001 266

Peptides are tiny messengers instructing our cells to perform specific processes, also known as cell signaling. What is Peptide Therapy