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In paracetamol overdose, a greater proportion of the dose is shunted to the oxidative pathway which results in greater NAPQI formation [13]

Cinelli, M

But we dont always know the best way to get these products into the body so they are used efficiently

Reelin has been linked to depression in preclinical models of depression: A decline in reelin expression in the hippocampal subgranular zone is associated with the emergence of depression-like behavior, and heterozygous reeler mice (HRM) with 50% of the normal levels of reelin are highly susceptible to the depressogenic effects of stress hormones (Lussier et al., 2011, 2013)

In small-molecule drug design, introducing a lysine moiety is usually intended to modulate the physicochemical properties of a compound