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Likewise, in HIV-infected myeloid cells, metabolic reprogramming during differentiation affects the redox state, which in turn can trigger or suppress latent virus ( Integration of metabolic and redox signals: role of TXNIP Thioredoxin-interacting protein (TXNIP) is an endogenous inhibitor of thioredoxin that binds to the reduced form of Trx and blocks its activity, thereby increasing intracellular ROS levels

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