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FSP1, another well-known suppressor of ferroptosis, acts independently of the ACSL4/GPX4 pathway

Metallomics 7 (2), 232243

GSTP1 mRNA and protein levels are decreased in the lens epithelium and cortex of patients with ARNC compared with age-matched controls, consistent with hypermethylation of GSTP1 promoter CpG islands, suggesting a potential role for GSTP1 epigenetic alterations in ARC lenses (235)

Research demonstrates that glutathione is the most abundant biothiol in the liver at approximately 10 mM concentration, where it undergoes conjugation reactions with toxic compounds through glutathione S-transferase (GST) enzymes

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