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Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

They share the same ultimate goal,supporting GH output, but do so through different mechanisms and with different pharmacokinetic profiles

Without high quality scientific studies in humans, including randomized controlled studies (RCTs), we simply do not know how these peptides will affect healing

Arch Intern Med 2010;170:143341

That small molecular size is the defining advantage: these peptide fragments can cross the blood-brain barrier and interact directly with neurons, something that most endogenous neurotrophic factors cannot do on their own