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10.1016/j.blre.2019.04.005 116 ShangJ.ChenW

In many cases, though, patients' disorders prevent them from absorbing the B12 unless it is administered by injection

Besides, Ca2+ activates Ca2+-dependent proteases, endonucleases, and phospholipases, which reinforces mitochondrial mechanisms of cell death.11,15 However, more subtle changes in hepatocanalicular function can occur at lower, non-necrotic levels of oxidative stress, and Ca2+ elevations also seem to play a key role