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Description

3 LC/MS/MS analytical workflow starts with a liquid chromatography instrument (HPLC) separating and concentrating sample components before reaching the MS

In fact, both systems share proteins (i.e., DNMT1) and ncRNAs (i.e., MALAT1, miR485 which are synthetized in the nucleus and shuttled in mitochondia and an alteration of one mechanism might modulate the other (87, 107)