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In low-risk healthy adults, the target should be set as part of a broader conversation about lifetime risk, not applied by default

Results were expressed as mean standard error of the mean (SEM), with each treatment group consisting of 812 mice [1]

This renders them predominantly effective in contexts where cancer cells have acquired resistance to cystine deprivation, such as through alternative amino acid transporters, upregulated transsulfuration pathways, or compensatory antioxidant networks (Du and Guo, 2022)

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