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Gene expression analysis showed 127 genes altered in a direction that shifts from tissue destruction patterns toward active repair, with repair genes upregulated and inflammatory genes downregulated simultaneously

Two subsequent sdAb-based radiotracers, [ 68 Ga]Ga-NOTA-Nb1053 and 18 F-labeled Nb1053, have been introduced for CD38-targeted immunoPET imaging for the early detection of MM [99, 109]

However, semaglutide is a single GLP-1 agonist, while retatrutide activates three receptor systems simultaneously, making direct comparisons problematic

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