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Canker Sores (Aphthous Ulcers) Canker sores (aphthous ulcers) are painful oral lesions distinct from cold sores they are not caused by herpes simplex virus and are believed to result from immune dysregulation, stress, trauma, or food sensitivities rather than viral infection [12][13]

Polyphenols and gut bacteria interact via mechanisms that affect metabolic regulation

doi: 10.3389/fimmu.2022.961708 Received 05 June 2022 Accepted 25 July 2022 Published 11 August 2022 Volume 13 - 2022 Edited by Lidan Zhao, Peking Union Medical College Hospital (CAMS), China Reviewed by Yuying Huang, University of Texas MD Anderson Cancer Center, United States

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