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(2024, October 9)

Toxins 13(4):286

The steroid hormones also signal through non-genomic mechanisms initiated at the cell membrane by palmitoylated steroid hormone receptor variants or GPCRs (e.g., G-protein coupled estrogen receptor 1, GPER1)

This agent works as a purine nucleoside phosphorylase inhibitor, a different mechanism than any of the medications to chronically lower uric acid described above

Whether any of this translates to cancer-preventive or anti-metastatic effects in living organisms is unknown, and cancer biology is far too complex for cell culture gene expression changes to predict clinical outcomes