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Vitamin D deficiency often presents as bone pain, muscle weakness, persistent fatigue, and low mood

J Nutr Biochem 2012;23(9):11551162

Upturn in metabolic rate results in over-production of free radicals, which in turn leads to oxidative stress damage such as lipid peroxidation, damage to proteins and nucleic acids and distortion of normal physiology in tissues 31

Regarding lipid profiles, Group II showed significant increases in triglycerides (TG), total cholesterol (TC), and LDL-C (P 0.001), alongside a non-significant decrease in HDL-C (P = 0.86) compared to Group I

Among the treatments currently being studied is the use of Cannabis sativa species, a plant that originated in Central Asia, was domesticated around 12,000 years ago, and has recently been used worldwide, including by the Chinese, Egyptians, Greeks, and Romans ( Cannabis sativa shows considerable potential for use, although further studies are needed to understand its properties and safety (Fordjour et al., 2023)