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Description

Therefore, these selective inhibitors drive significant conformational changes of Rv1098c, and then competitively prevent the substrate and inhibitor from binding at the neighboring active sites by locking the subunits in the open conformation

E., East, M

& Shabab, B

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Life Sci 351:122838 Hglinger GU, Adler CH, Berg D, Klein C, Outeiro TF, Poewe W, Postuma R, Stoessl AJ, Lang AE (2024) A biological classification of Parkinsons disease: the SynNeurGe research diagnostic criteria