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Physicians typically begin with a low dose, observe the response and side effects, then titrate upward if necessary

But what I'm saying is that just the concept of getting all these things out of our food supply, making people healthy, getting people off of all these prescription drugs, making people more metabolically healthy, we're so stupid with our tribal shit that just

However, cardiac arrest was observed in 10% (3 out of 30) of patients with advanced solid tumors receiving a dose of 12 mg/kg in a dose-escalation trial of Sym004 (a 1:1 mixture of cetuximab and panitumumab), which was regarded as an incidental finding [280]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Walmsley SR, Cowburn AS, Clatworthy MR, Morrell NW, Roper EC, Singleton V, Maxwell P, Whyte MK, Chilvers ER