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Thus, the Rasch-based method for developing weighted scales was applied to questions related to activities of daily living in patients with ALS to create the 28-question Rasch-built Overall ALS Disability Scale (ROADS) [35, 36]

5.4 Use in Women of Childbearing Potential Because of the risk to the fetus of decreased IQ, neurodevelopmental disorders, and major congenital malformations (including neural tube defects), which may occur very early in pregnancy, valproate should not be administered to a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable

In some reverse cholesterol transport experiments, mice were treated with a cocktail of oral antibiotics (as in atherosclerosis studies described above) for 4 weeks prior to enrollment

doi: 10.1002/ajmg.a.37144 72

These drugs are commonly used to treat high blood pressure levels, but are also effective in relieving symptoms associated with hyperthyroidism such as tremors, rapid heart rate, and heart palpitations