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Proc Natl Acad Sci USA 2011;108:95729577

It is produced by a mitochondrial gene, and it has been shown to play a key role in signaling and energy productionrestores homeostasis by initiating catabolic process for ATP production decreases insulin resistance[and] increases athletic performance (Seeds, 2020)

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The combination of peptides with other therapies, such as gene therapy or immunotherapy, holds the potential for more effective treatments for complex diseases

In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected